Is oxybutynin sedating intimidating wikihow
Sometimes, that drowsiness is why people take the drugs, and a little sedation might sound benign.But if your brain is older, or otherwise vulnerable, don’t underestimate these drugs.And even if you are super-fit and never take any medications, it’s good to know what to help your friends and family avoid.Research has linked the drugs to increased risk of Alzheimer’s disease and also to hospitalizations in older adults.Anticholinergics used for hyperhidrosis include propantheline, glycopyrronium bromide, oxybutynin, and benztropine. Anticholinergic therapy is generally not recommended in patients with glaucoma (especially narrow-angle glaucoma) and those who have impaired gastric emptying or a history or symptoms of urinary retention.Patients should be aware of risks of overheating when using anticholinergics.
It should be noted that studies (in JAMA Neurology 2016 and JAMA Internal Medicine 2015) have reported a potential link between the development of dementia and/or brain atrophy and long-term, high-level anticholinergic use in patients over the age of 65.
The drugs literally have the opposite effect of medications often used to treat Alzheimer’s. These include the strong antihistamines hydroxyzine (brand name Vistaril) and diphendyramine (brand name Benadryl), which are often prescribed for itching or hives. (These are also prescribed to reduce the chance of chronic nerve pain after shingles.) Commonly-used tricyclics include amitriptyline and nortriptyline. Many more medications have strong anticholinergic effects, but they tend to be prescribed less often.
Donepezil (brand name Aricept), for example, the neurotransmitter acetylcholine by blocking the brain enzyme that breaks it down. Ask your doctor or pharmacist if you want help spotting all anticholinergics you might be taking.
So for better brain health, it’s definitely worth learning to spot these drugs and avoid them. Meclizine (brand name Antivert) is often prescribed to treat benign positional vertigo. You should especially avoid or minimize anticholinergics if you: If you’re younger and have a healthier brain, in the short-term, anticholinergics might just make you drowsy and maybe a little unsteady on your feet.
Here are seven common types of anticholinergic drugs: 1. The prime example is diphenhydramine (brand name Benadryl), which is available over-the-counter and has strong anticholinergic activity. Most OTC painkillers, such as acetaminophen and ibuprofen (brand names Tylenol and Motrin, respectively) come in a “PM” or night-time formulation, which means a mild sedative — usually an antihistamine — has been mixed in. These include bladder relaxants such as oxybutynin and tolterodine (brand names Ditropan and Detrol, respectively). But research suggests that anticholinergics are basically a low-level toxin for the brain and cumulative exposure can add up to definite harm.